Gerardo Guillén Selected Research

Vaccines

1/2022	A recombinant SARS-CoV-2 receptor-binding domain expressed in an engineered fungal strain of Thermothelomyces heterothallica induces a functional immune response in mice.
1/2019	Safety and Therapeutic Profile of a GnRH-Based Vaccine Candidate Directed to Prostate Cancer. A 10-Year Follow-Up of Patients Vaccinated With Heberprovac.
1/2019	A heterologous prime-boost strategy for immunization against Dengue virus combining the Tetra DIIIC subunit vaccine candidate with the TV005 live-attenuated tetravalent vaccine.
1/2019	Aiming at the heart: the capsid protein of dengue virus as a vaccine candidate.
1/2018	Cross-validation Studies of a Novel Low-cost Hepatitis B Virus Quantitative Polymerase Chain Reaction System.
1/2016	Dengue encephalitis-associated immunopathology in the mouse model: Implications for vaccine developers and antigens inducer of cellular immune response.
8/2015	A novel tetravalent formulation combining the four aggregated domain III-capsid proteins from dengue viruses induces a functional immune response in mice and monkeys.
7/2014	Type I interferon signals in macrophages and dendritic cells control dengue virus infection: implications for a new mouse model to test dengue vaccines.
7/2014	Generation and characterization of potential dengue vaccine candidates based on domain III of the envelope protein and the capsid protein of the four serotypes of dengue virus.
5/2014	Capsid protein: evidences about the partial protective role of neutralizing antibody-independent immunity against dengue in monkeys.

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Gerardo Guillén Research Topics

Disease

28	Dengue (Dengue Fever) 01/2016 - 08/2003
11	Infections 01/2023 - 01/2008
5	Viremia 01/2019 - 08/2003
3	COVID-19 01/2022 - 02/2021
3	Neoplasms (Cancer) 02/2021 - 12/2005
3	Virus Diseases (Viral Diseases) 06/2017 - 02/2010
2	Prostatic Neoplasms (Prostate Cancer) 01/2019 - 01/2008
2	Viral Encephalitis 01/2016 - 04/2009
2	Encephalitis (Encephalitis, Rasmussen) 01/2016 - 01/2013
2	Necrosis 06/2012 - 02/2007
1	Vesicular Stomatitis 06/2023
1	Pneumonia (Pneumonitis) 02/2021
1	Severe Dengue 01/2019
1	Hepatitis B 01/2018
1	Reinfection 06/2017
1	Meningococcal Infections 02/2010
1	Breast Neoplasms (Breast Cancer) 01/2008
1	Myocardial Infarction 02/2007
1	Body Weight (Weight, Body) 02/2007
1	Coronary Occlusion 02/2007
1	Ulcer 09/2006
1	Diabetic Foot 09/2006
1	Wounds and Injuries (Trauma) 09/2006
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 12/2005

Drug/Important Bio-Agent (IBA)

24	VaccinesIBA 01/2022 - 08/2003
21	Proteins (Proteins, Gene)FDA Link 12/2021 - 08/2003
9	Neutralizing AntibodiesIBA 01/2019 - 08/2003
9	Capsid Proteins (Capsid Protein)IBA 06/2017 - 01/2007
7	AntibodiesIBA 06/2023 - 08/2003
7	Recombinant ProteinsIBA 07/2014 - 01/2008
5	Antiviral Agents (Antivirals)IBA 06/2017 - 01/2007
5	Recombinant Fusion ProteinsIBA 07/2012 - 04/2006
4	Dengue VaccinesIBA 07/2014 - 04/2009
3	AntigensIBA 01/2023 - 01/2013
3	Carrier Proteins (Binding Protein)IBA 06/2011 - 02/2009
2	Peptides (Polypeptides)IBA 02/2021 - 12/2005
2	Gonadotropin-Releasing Hormone (GnRH)FDA Link 01/2019 - 01/2008
2	Interferon-gamma (Interferon, gamma)IBA 07/2014 - 06/2012
2	Combined VaccinesIBA 07/2014 - 06/2012
2	Viral AntigensIBA 07/2012 - 12/2008
2	EpitopesIBA 07/2012 - 12/2008
2	Immunoglobulin M (IgM)IBA 01/2008 - 08/2003
2	Amino Acids FDA Link 10/2006 - 01/2004
1	Subunit VaccinesIBA 12/2021
1	Protein Kinases (Protein Kinase)IBA 02/2021
1	Testosterone (Sustanon)FDA Link 01/2019
1	aluminum sulfate (alum)IBA 01/2015
1	OligodeoxyribonucleotidesIBA 01/2015
1	Interferon Type IIBA 07/2014
1	Immunoglobulin G (IgG)IBA 07/2012
1	CytokinesIBA 06/2012
1	Polysaccharides (Glycans)IBA 05/2012
1	Indicators and Reagents (Reagents)IBA 12/2009
1	Hormones (Hormone)IBA 01/2008
1	AndrogensIBA 01/2008
1	Oxidants (Oxidizing Agents)IBA 02/2007
1	Saline SolutionIBA 02/2007
1	gamma- aminobutyryl- 2- methyltryptophyl- 2- methyltryptophyl- 2- methyltryptophyl- lysinamideIBA 02/2007
1	Epidermal Growth Factor (EGF)IBA 09/2006
1	Glycoproteins (Glycoprotein)IBA 08/2003

Therapy/Procedure

1	Therapeutics 01/2019
1	Surgical Amputation (Amputations) 09/2006
1	Immunotherapy 12/2005